Selected publications

L-plastin enhances NLRP3 inflammasome assembly and bleomycin-induced lung fibrosis

March 15, 2022

Joshi H, Almgren-Bell A, Anaya EP, Todd EM, Van Dyken SJ, Seth A, McIntire KM, Singamaneni S, Sutterwala F, Morley SC. L-plastin enhances NLRP3 inflammasome assembly and bleomycin-induced lung fibrosis. Cell Rep. 2022 Mar 15;38(11):110507. doi: 10.1016/j.celrep.2022.110507. PMID: 35294888; PMCID: PMC8998782.

Novel mouse model reveals that serine phosphorylation of l-plastin is essential for effective splenic clearance of pneumococcus

May 1, 2021

Anaya EP, Lin X, Todd EM, Szasz TP, Morley SC. Novel Mouse Model Reveals That Serine Phosphorylation of L-Plastin Is Essential for Effective Splenic Clearance of Pneumococcus. J Immunol. 2021 May 1;206(9):2135-2145. doi: 10.4049/jimmunol.2000899. Epub 2021 Apr 15. PMID: 33858961; PMCID: PMC8323710.

Recovery from COVID-19 in a Child with Chronic Granulomatous Disease and T Cell Lymphopenia

October 8, 2020

Mantravadi V, Nguyen ST, Morley SC, Bednarski JJ, Kitcharoensakkul M, Cooper MA. Recovery from COVID-19 in a Child with Chronic Granulomatous Disease and T Cell Lymphopenia. J Clin Immunol. 2021 Jan;41(1):23-25. doi: 10.1007/s10875-020-00896-2. Epub 2020 Oct 27. PMID: 33108551; PMCID: PMC7588587.

miR-125a-5p regulates megakaryocyte proplatelet formation via the actin-bundling protein L-plastin

October 27, 2020

Bhatlekar S, Manne BK, Basak I, Edelstein LC, Tugolukova E, Stoller ML, Cody MJ, Morley SC, Nagalla S, Weyrich AS, Rowley JW, O’Connell RM, Rondina MT, Campbell RA, Bray PF. miR-125a-5p regulates megakaryocyte proplatelet formation via the actin-bundling protein L-plastin. Blood. 2020 Oct 8;136(15):1760-1772. doi: 10.1182/blood.2020005230. PMID: 32844999; PMCID: PMC7544541.

The Association of Medications and Vaccination with Risk of Pneumonia in Inflammatory Bowel Disease

May 12, 2020

Gregory MH, Ciorba MA, Wiitala WL, Stidham RW, Higgins P, Morley SC, Hou JK, Feagins LA, Govani SM, Cohen-Mekelburg SA, Waljee AK. The Association of Medications and Vaccination with Risk of Pneumonia in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2020 May 12;26(6):919-925. doi: 10.1093/ibd/izz189. PMID: 31504531; PMCID: PMC7350553.

Neutrophil L-Plastin Controls Ocular Paucibacteriality and Susceptibility to Keratitis

April 3, 2020

Lu X, Kugadas A, Smith-Page K, Lamb J, Lin T, Ru Y, Morley SC, Fichorova R, Mittal SK, Chauhan SK, Littleton S, Saban D, Gadjeva M. Neutrophil L-Plastin Controls Ocular Paucibacteriality and Susceptibility to Keratitis. Front Immunol. 2020 Apr 3;11:547. doi: 10.3389/fimmu.2020.00547. PMID: 32318063; PMCID: PMC7147296.

L-Plastin deficiency produces increased trabecular bone due to attenuation of sealing ring formation and osteoclast dysfunction

January 22, 2020

Chellaiah MA, Moorer MC, Majumdar S, Aljohani H, Morley SC, Yingling V, Stains JP. L-Plastin deficiency produces increased trabecular bone due to attenuation of sealing ring formation and osteoclast dysfunction. Bone Res. 2020 Jan 22;8:3. doi: 10.1038/s41413-019-0079-2. PMID: 31993243; PMCID: PMC6976634.

Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia

August 14, 2019

Todd EM, Ramani R, Szasz TP, Morley SC. Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia. Sci Adv. 2019 Aug 14;5(8):eaax3387. doi: 10.1126/sciadv.aax3387. PMID: 31453341; PMCID: PMC6693910.

Alveolar macrophage development in mice requires L-plastin for cellular localization in alveoli

December 15, 2016

Todd EM, Zhou JY, Szasz TP, Deady LE, D’Angelo JA, Cheung MD, Kim AH, Morley SC. Alveolar macrophage development in mice requires L-plastin for cellular localization in alveoli. Blood. 2016 Dec 15;128(24):2785-2796. doi: 10.1182/blood-2016-03-705962. Epub 2016 Oct 6. PMID: 27758872; PMCID: PMC5159703.

Complete bibliography